From photons to
drug development
Complete characterization in a single acquisition. Built for lipid nanoparticles and extracellular vesicles, Optomics® is also scalable to other complex nanotherapeutics.
The bottleneck
The characterization bottleneck is costing you time at every stage. Nanotherapeutics are transforming medicine, but characterizing them remains one of the most stubborn constraints in the pipeline.
What the tools do today
Destructive processing.
Single parameter instruments.
Complex outputs.
Each tool measures one parameter at a time. DLS gives you sizebut not payload. TEM gives you morphology ut consumes the sample and takes hours. NTA adds concentrationas another separate run. Meanwhile, batch inconsistencies accumulate, reagent waste compounds, and R&D decision cycles stretch.
The result
A bottleneck that delays formulation down-selection, increases cost per iteration, and pushes timelines back at precisely the stage where speed matters most.
vs.
What Optomics® does instead
Intact samples.
Multiparametric analyses.
Automated results.
A single spectroscopic acquisition delivers simultaneous data on particle size, concentration, and payload distribution, in minutes, without consuming the sample. The same formulation continues downstream, eliminating sequential destructive workflows.
the result
30–50%
faster time-to-results. 25% less reagent waste. Formulation decisions made at the right stage — not forced by sample depletion.
Traditional tools
DLS · TEM · NTA
Optomics®
Spectroscopic AI
Sample state
Destructive — sample lost
Non-destructive — sample preserved
Parameters / run
Single parameter only
Simultaneous: size, concentration, payload
Time to result
Hours per parameter
Minutes per acquisition
Throughput
Low — sequential workflows
High — parallel multimodal readout
Batch consistency
Manual cross-referencing required
Automated, real-time QC flag
R&D cycle impact
Bottleneck at every formulation iteration
30–50% faster time-to-results
Optomics®
vs. traditional
characterization tools
A direct comparison across the parameters that matter to formulation and QC workflows.
Traditional tools
DLS · TEM · NTA
Optomics®
Spectroscopic AI
Sample state
Destructive — sample lost
Non-destructive — sample preserved
Parameters / run
Single parameter only
Simultaneous: size, concentration, payload
Time to result
Hours per parameter
Minutes per acqui
Throughput
Low — sequential workflows
High — parallel multimodal readout
Batch consistency
Manual cross-referencing required
Automated, real-time QC flag
Reagent dependency
Reagents required for many assays
Label-free — no consumable dependency
R&D cycle impact
Bottleneck at every formulation iteration
30–50% faster time-to-results
How Optomics® fits pharma R&D
From formulation sample to decision. In one run.
Sample input
Spectral Scan
AI analysis
Decision output
Application
Where Optomics® changes the formulation math
LNP formulations require multi-parameter characterization at every development stage, from initial screening through batch release. Traditional sequential workflows create compounding delays: with different methods being required to determine critical sample attributes like size, drug encapsulation and surface charge.
The cost of the bottleneck
Delayed formulation down-selection. Reagent-intensive parallel assays. Batch inconsistencies that only surface late in the pipeline, when correction is costly and timeline impact is maximal.
The Optomics® solution
A single non-destructive acquisition delivers simultaneous data on particle size, concentration, and payload distribution - enabling real-time batch comparison and formulation QC without sequential workflows or sample sacrifice.
Current methods fail to provide a complete and accurate characterization of heterogenous EVs.
Molecular content
Comprehensive analysis of the molecular composition is technically challenging and laborious, with results that are often difficult to integrate.
Physical parameters
Size and particle number concentration measurements are inaccurate due to the inherent sample heterogeneity.
The Optomics® solution
Optomics® characterizes EVs and LNPs in their native form — delivering precise, multiparametric profiles of size, concentration, and RNA cargo composition and distribution from a single acquisition, without destroying or preprocessing the sample.
The shared engine
One engine.
Two ends of the same pipeline.
Biopharmaceutical analytics
Clinical
Screening
More technical deep-dive on iLOF’s application note. Download it below.
Everything a scientist needs to evaluate Optomics integration in their workflow: methodology, validation datam and performance benchmarks.
Read the technical evidence behind Optomics®
Application notes, validation data, and methodology in one document.
Want to discuss your specific workflow?
Our team works directly with pharma R&D scientists to scope integration and technical fit.
